Located on the banks of the Tennessee River, Muscle Shoals, Alabama is the unlikely breeding ground for some of the most creative and defiant music in American history. Under the spiritual influence of the "Singing River" as Native Americans called it, the music of Muscle Shoals is some of the most important and resonant of all time. "I'll Take You There", "Brown Sugar", "When a Man Loves a Woman", "I Never Loved a Man the Way That I Loved You", "Mustang Sally", "Tell Mama", "Kodachrome", and "Freebird" are just a few of the tens of thousands of tracks created there. At it's heart is Rick Hall who founded FAME Studios. Overcoming crushing poverty and staggering tragedies, he brought black and white musicians together to create music that would last for generations while also giving birth to the unique 'Muscle Shoals sound' and the rhythm section 'The Scampers'. in this movie legendary artists including Aretha Franklin, Greg Allman, Bono, Clarence Carter, Jimmy Cliff, Mick Jagger, Etta James, Alicia Keys, Wilson Pickett, Keith Richards, Percy.